International Kidney Disease Guidelines were recently modified to advise caution over the use of Warfarin, an anticoagulant (blood thinner) used to prevent heart attacks, strokes, and blood clots; in patients with Chronic Kidney Disease (CKD) because of their increased bleeding risk. This was a very serious warning. Nephrologists began cutting back on Warfarin prescriptions due to fear that the drug may cause severe bleeding which may be life-threatening, and even lead to death.
Well, a very recent study, published in the Journal of the American Medical Association on March 5th, 2014 found that, "The benefits of anticoagulation with Warfarin outweigh the risks in patients with Chronic Kidney Disease, even for those with the most severe kidney damage (End Stage Renal Disease)." Researchers showed that Warfarin treatment reduced the risk of thrombotic events (blood vessel clotting in any part of the circulatory system such as the heart, arteries, veins, or capillaries) in those with CKD, without increasing their risk of bleeding.
Quickly grab a pen and write down the following important information to share it with your Nephrologists. The Swedish study included 24,317 patients, 5,292 (21.8%) of whom were treated with Warfarin and 12,583 (51.7%) of whom had CKD stage 3 or worse. Over 12 months of follow-up, the patients treated with Warfarin had an 18% lower relative risk of having a heart attack, stroke or deadly thrombotic event than untreated patients with the same risk of hemorrhage. The pattern only improved in later stages with stage 5 realizing a 20% lower risk of negative side effects without an increase in bleeding risk.
Now, what should you do with this information? Well, start by taking the paper you wrote on to the next meeting with your Nephrologists and ask them if Warfarin is a better treatment for you than your current blood thinner. If you are satisfied with your current treatment and do not want to try another, keep this information for later use.
Recommended Reading: A New Weapon Found To Fight The Effects Of Chronic Kidney Disease And Diabetes
Thanks for stopping by KidneyBuzz.com. We are here every day offering FREE News & Information that teaches those with Chronic Kidney Disease how to better manage their lives. You are encouraged to take advantage of our other resources as well, such as our guide to help you save on monthly medications, How To Save $190.00 or More On Monthly Medications.
Most Popular Stories:
"Anticoagulation with Warfarin Beneficial in Patients with CKD." Http://www.pulsetoday.co.uk/. PULSE: At the Heart of General Practice since 1960.
Ravi Shah and Rif Rahman. "Warfarin Beneficial in Chronic Kidney Patients with Atrial Fibrillation." Http://www.2minutemedicine.com/. 2minutemedicine.com.
"Warfarin, Kidney Dysfunction, and Outcomes Following Acute Myocardial Infarction in Patients With Atrial Fibrillation." Https://jama.jamanetwork.com/. JAMA Network.
"Warfarin: MedlinePlus Drug Information." Http://www.nlm.nih.gov/. U.S. National Library of Medicine.