New Breakthrough For Commonly Used Dialysis Drug Could Be A Game Changer For CKD Patients

heparin_C.F.-04.09.03.jpg

Researchers at the University of North Carolina, Chapel Hill (UNC) have created a synthetic form of Heparin (blood thinning medication) noted the journal, Nature Chemical Biology. Since the late 1930s, Heparin has been used as an anticoagulant (blood thinner), and is most commonly extracted from pig intestines. It prevents blood clots from forming and is most often used during and after such procedures as dialysis by Chronic Kidney Disease (CKD) patients, heart bypass surgery, stent implantation, and knee and hip replacement. Its side effects can include uncontrolled bleeding and thrombocytopenia (too few platelets in the blood). This new synthetic version of Heparin can decrease risks and side effects of the naturally developed drug.

Recommended Reading: Is Use of Heparin in Dialysis as Safe as Dialysis without Heparin?

"Whenever you mix the food chain and the drug chain together, you end up with potential for disaster," said leading researchers. The natural form of the Heparin was in the spotlight in spring 2008 when more than 80 people died and hundreds of others suffered adverse reactions to the drug, leading to recalls of Heparin in countries around the world. Authorities linked the outbreak to a contaminant in raw natural Heparin from China.

Recommended Reading: How Chronic Kidney Disease Patients Can Reduce The Risk Of Bleeding-Out, Fistula Failure And Worse

Whether it comes from contamination, viruses, prions (infectious protein particles), or other adulterations (impurities) any drug including Heparin is much more dangerous when you make it in an uncontrolled environment. Robert Linhardt, lead researcher and one of the inventors of the new drug said, "The synthetic version that we've made is reversible, it can be used in renal patients, and it doesn't come from animals, which is a critical advance in safety."

Recommended Reading: Ways to Prevent and Treat Infiltration of Your Fistula caused by a Dialysis Needle Stick

Up to 5 percent of patients receiving heparin experience some form of uncontrolled bleeding. Naturally produced Heparin is cleared from the body by the kidneys, which can make it more dangerous for patients with a weakened renal system, a relatively common condition among patients requiring anticoagulation. The new changes allow the synthetic version of the drug to bind to receptors that clear through the liver; making it safer for dialysis patients.

Recommended Reading: Eliminating The Serious Concern Of Blood Clots For Those With Chronic Kidney Disease 

Visit KidneyBuzz.com for Breaking News & Information every day. We appreciate your support, and hope that you sign up for our free newsletter containing exclusive news and information that assists Chronic Kidney Disease and Diabetic patients live a long and high quality life. 

Most Popular Stories:

Itching At Fistula Access And How Chronic Kidney Disease Patients Can Safely Correct That Problem
Misinformation About Cancer Affecting The Chronic Kidney Disease Community
Artificial Kidney Holds Promise for those Afflicted with ESRD

References:

Martialay, Mary L. "Researchers Create Synthetic Version of Heparin for Use in Kidney Patients." Http://medicalxpress.com/. Medical Xpress.

"Synthetic Version of Heparin Created for Use in Kidney Patients." Http://www.sciencedaily.com/. ScienceDaily.

PURCHASE YOUR $5.00 "NO BLOOD PRESSURE (BP)/NO NEEDLE STICK (STICK)" MEDICAL ALERT BRACELET.CLICK HERE.

PURCHASE YOUR $5.00 "NO BLOOD PRESSURE (BP)/NO NEEDLE STICK (STICK)" MEDICAL ALERT BRACELET.CLICK HERE.

Woman's Dialysis T-Shirt. Click Here. 

Woman's Dialysis T-Shirt. Click Here. 

PURCHASE YOUR $5.00 DIET AND LIFE MANAGEMENT GUIDE TO SUPPORT KIDNEYBUZZ.COM AND IMPROVE YOUR HEALTH OUTCOMES. CLICK HERE. 

PURCHASE YOUR $5.00 DIET AND LIFE MANAGEMENT GUIDE TO SUPPORT KIDNEYBUZZ.COM AND IMPROVE YOUR HEALTH OUTCOMES. CLICK HERE. 

DIALYSIS IS A BIG PAIN IN THE A_ _ T-SHIRT (ARM, BUT I LIKE THE WAY YOU THINK). CLICK HERE.

DIALYSIS IS A BIG PAIN IN THE A_ _ T-SHIRT (ARM, BUT I LIKE THE WAY YOU THINK). CLICK HERE.

Dialysis Damned If You Do, Dead If You Don't! Dialysis Shirt. Click Here.

Dialysis Damned If You Do, Dead If You Don't! Dialysis Shirt. Click Here.