According to researchers, individuals with kidney disease have more risk of periodontal disease due to lower levels of vitamin D, than individuals with regular levels of vitamin D. Also, patients diagnosed with periodontitis tended to have higher levels of Interleukin-6 (a marker of inflammation), than patients without periodontitis. Furthermore, they found, patients with periodontitis tended to have lower levels of cathelicidin (an antimicrobial protein that serves as a natural antibiotic). Compared to patients with healthy gums.
Vitamin D deficiency is associated with chronic periodontitis in patients with kidney disease not yet on dialysis. This association seems to be mediated through an impairment in clearing bacterial infection due to a decrease in cathelicidin production.
An individual with kidney disease who has low vitamin D levels, also has low cathelicidin levels, and this predisposes him/her to have high frequency of periodontitis as well as a higher level of severity of gum disease.
This study reaches the reasonable conclusion that the lack of vitamin D can lead to periodontal problems. This is something worth giving further consideration, and should be discussed with your healthcare team to be included in your treatment plan.Read more: http://www.medpagetoday.com/MeetingCoverage/NKF/38254