Functioning Human Mini-Kidneys Push Kidney Regeneration Forward For CKD And Dialysis Patients



Many Chronic Kidney Disease and Dialysis patients have asked, "What is the status of Kidney Regeneration? Is there any progress, and will we ever see this technology? 

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For Chronic Kidney Disease and Dialysis patients, Kidney Regeneration is, of course, the Holy Grail of Treatment Options. “The kidney actually ranks very highly in its ability to repair itself,” said Dr. Joseph Bonventre (Professor of Medicine at Harvard Medical School). Hence, harnessing the power of the kidney’s innate ability to regenerate could enable patients to regain their health, improve their quality of life and get off of Dialysis. That is why news about functioning Human Mini-Kidneys shows progress for a much-desired breakthrough. 

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When kidneys are damaged beyond repair, the only options for patients currently are Dialysis or Kidney Transplantation which is severely restricted due to the scarcity of Kidney Donors. Since Dialysis is a terrible burden and very limiting for most patients (over 600,000+ in the U.S.) who are tethered to their machines for hours daily or for several times during the week, Kidney Regeneration would be a welcomed alternative. 

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Although there are Artificial Kidneys that are being developed, The kidney has multiple functions that cannot be fully replicated: Homeostasis (balance of many body functions), control of blood pressure, production of red blood cells, and elimination of waste (from food, medication or toxic substances), Artificial Technology cannot recreate the multiple functions of a natural kidney:  Homeostasis (balance of many body functions), control of blood pressure, production of red blood cells, and efficiently elimination of waste (from food, medication or toxic substances), while keeping a proper balance of essential substances, fluids and minerals in the body.

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That is why the breakthrough of Mini-Kidneys, which accurately represent Human Kidneys for replacement therapies, bridges a critical gap between animal models and human applications and progresses Kidney Repair (Regeneration) for Chronic Kidney Disease and Dialysis patients.

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According to Harvard Stem Cell Institute, "Patients might not have to wait too long to see the benefits of this research." In fact, for the first time a patient has had a Mini-Kidney regenerated from their stem cells in Australia.

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In the study published in the American Journal of Human Genetics, stem cells derived from a child with genetic kidney disease were grown into two sets of living Mini-Kidneys outside of the body. The stem cells were created from a skin biopsy taken from a 12-year-old suffering with kidney complications. Identifying methods to take that technology back inside the body would allow the extensive regeneration that the kidney is unable to do on its own.

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Human Mini-Kidney Regeneration is a promising step forward for patients. Like and share this article with others so that they are aware of the inspiring and uplifting progress. will continue to follow Kidney Regeneration Breakthroughs along with other Dialysis alternatives and provide updates and insights. To get the latest information, join our email list by completing the below form:

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