Switching from intravenous (IV) to oral activated vitamin D may offer more effective control of hyperparathyroidism (over-activity of the parathyroid) in Chronic Kidney Disease (CKD) patients, specifically those on Hemodialysis (HD), according to a new Canadian study.
Vitamin D deficiency and insufficiency are universal in HD patients resulting in depression, loss of appetite, nausea, vomiting, constipation, bone disease and severe Cardiovascular risk.
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The study, led by Dr. Michel Vallée of Hôpital Maisonneuve-Rosemont (Montreal), found that giving CKD patients vitamin D orally three times a week during HD sessions helped to decrease hyperparathyroidism significantly from 80 to 59 pmol/L and total serum calcium levels increased significantly from 2.34 to 2.40 mmol/L. What's more is that the vitamin D dosages were significantly reduced. It is always good to minimize the amount of medicine that goes into your body if at all possible.
Recommended Reading: Hyperparathyroidism on CKD can have debilitating effects, especially Bone Disease
With respect to overall health outcomes, researchers noted that even an "intermittent" (alternating) oral administration of vitamin D is more effective than only administering the medication through IV dosages. Hence, this is a really simple and straightforward way that HD patients can directly improve their health outcomes. Talk to your Nephrologists about taking your vitamin D medication orally.
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Jody A. Charnow. "Hemodialysis Patients Benefit More from Oral than IV Vitamin D." Renalandurologynews.com. Renal Urology News.
Bansal, Beena, Shyam Bansal, Ambrish Mithal, Vijay Kher, and Raman Marwaha. "Vitamin D Deficiency in Hemodialysis Patients." National Center for Biotechnology Information. U.S. National Library of Medicine.