BRAND NEW UPDATE: Artificial Kidney Holds Promise for those Afflicted with ESRD

UPDATE: In talking with Chronic Kidney Disease patients, a common question is, "How long will the Artificial Implantable Kidney device last after implantation?" Others ask, "Will the Artificial Implantable Kidney have to be replaced?"

Well, in a recent update the Research Team for the Kidney Project (developers of the Artificial Implantable Kidney) answered this question. They suggested that, "The device is meant to be permanent..." In fact, their research found that it could be possible for the device to operate for many years, without failure. However, "if failures occur, the replacement of the filter and/or cells would involve a minimally invasive surgery," said Researchers. Sign up for the Kidney Projects database of names to be considered for the expected 2017 Human Trials.

PREVIOUS UPDATE (12/13): Since the last University of California, San Francisco (UCSF) update on November 14th, 2014, the Community has asked in overwhelming numbers, "When will the Artificial Kidney be ready for transplant?" Well, Lead Researcher, Dr. Shuvo Roy, UCSF School of Pharmacy announced that they estimate the clinical trials will be completed in approximately 5 years, by the year 2020. "Once the clinical trials are complete," Dr. Roy said, "the device will be immediately available for patients."  

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It is incredibly exciting to consider the likelihood of having an Implantable Artificial Kidney readily available for Transplantation in just 5 short years, wouldn't you agree? This may completely eliminate the need for a Kidney Transplant Waiting List. The UCSF "Kidney Project" team will work with manufacturers to discuss and manage the details of production and distribution during the clinical trials. 

Dr. Roy also addressed naysayers (those who express negative or pessimistic views) who suggested that the Artificial Implantable Kidney is an impractical idea and said that they are "out of date by a decade or more." The doctor further wrote, "The Kidney Project is a multicenter, multidisciplinary team effort involving basic scientists, engineers, veterinarians, physicians, and regulatory agencies. We have taken this project from the idea that Dr. Fissell and I conceptualized in 1999 to bench testing and now, as reported at this year's American Society of Nephrologists (ASN) Kidney Week conference, sustained testing of the technology in animals." believes that there is a lot of hope to be had for the Chronic Kidney Disease Community and Dialysis, Friends. However, what are your thoughts? Are you ready for the Artificial Implantable Kidney Transplant? Click here and join the lively discussion at the Facebook Fan Page right now to share your thoughts and/or concerns. Be sure to also share this information with you Friends on Facebook and Followers on Twitter. Moreover, complete the below form for information on the expected 2017 Artificial Implantable Kidney Transplant Human Trials and how to sign up. Be sure to sign up sooner rather than later! 


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PREVIOUS UPDATE (11/14): Knowing that the Artificial Implantable Kidney is Fast Tracked by the Food and Drug Administration (FDA), many have asked, "What are the criteria for choosing the first group of Chronic Kidney Disease patients with Kidney Failure for Human Trials? 

Well on Monday, November 17th, 2014 the University of California, San Francisco's Kidney Project lead Researchers answered this question and said, "For the initial clinical trials, we will mainly be looking for patients who exhibit high levels of antibodies and have been on the transplant wait list for a long time."

We love hearing from all members in the community so join the conversation and share your general thoughts, questions or concerns about the Kidney Project and the Program's Human Trials Criteria at the Facebook Fan Page by clicking here.

ORIGINAL: Shuvo Roy, PhD, UCSF School of Pharmacy and William Fissell, MD, Vanderbilt University Medical Center and the project's medical director, are two key contributors to the UCSF-led effort to create an implantable artificial kidney for dialysis patients.

This device will be used to treat individuals with end-stage renal disease (ESRD). Affecting 2 million people worldwide, ESRD (chronic kidney failure) is fatal unless treated. And while transplantation is the most effective treatment option, donor organs are in short supply. Further, kidney dialysis can be a limiting and costly treatment for the afflicted individual.

“We can provide an alternative therapy and a treatment option that doesn't exist today for the vast majority of people today that are forced to rely on dialysis,” Roy said. The artificial kidney project aims to enable patients with chronic kidney failure to lead healthier and more productive lives, without external dialysis or immune suppressant medication.

Kidney Project Put on Fast-Track by FDA

Last year, the artificial kidney project was selected as one of the first projects to undergo more timely and collaborative review at the Food and Drug Administration (FDA). The device targeted for clinical trials in 2017.

The UCSF artificial kidney, or implantable Renal Assist Device (iRAD) would include thousands of microscopic filters as well as a bioreactor to mimic the metabolic and water-balancing roles of a real kidney.

The combined treatment has been proven to work for the sickest patients using a room-sized external model developed by a team member at the University of Michigan. Roy’s goal is to apply silicon fabrication technology, along with specially engineered compartments for live kidney cells, to shrink that large-scale technology into a device the size of a coffee cup. The device would then be implanted in the body, allowing the patient to live a more normal life.

For more information on kidney transplant and kidney care visit, Kidney Coach.

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